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Author : Tang, Man-Lai; Pei, Yanbo; Wong, Weng-Kee; Li, Jian-Liang
Category : Journal Article
Department :
Year / Month : 2012
ISSN: 0962-2802
Source : Statistical Methods in Medical Research, 21, 331 - 345

Abstract

    We review a few popular statistical models for correlated binary outcomes, present maximum likelihood estimates for the model parameters, and discuss model selection issues using a variety of goodness-of-fit test statistics. We apply bootstrap strategies that are computationally efficient to evaluate the performance of goodness-of-fit statistics and observe that generally the power and the type I error rate of the goodness-of-fit statistics depend on the model under investigation. Our simulation results show that careful choice of goodness-of-fit statistics is an important issue especially when we have a small sample and the outcomes are highly correlated. Two biomedical applications are included.